Canine atopic dermatitis, acute moist, allergic rhinitis, allergic conjunctivitis, and chronic diarrhea often refer to Type I hypersensitivity. However, Type I hypersensitivity do not always show specific or typical clinical signs, and therefore can lead to misdiagnosis.
Total immunoglobulin E (tIgE) in the blood is increased in Type I hypersensitivity. Our “Canine Allergic Tendency Reference Test” can detect increased tIgE levels in dog serum in 10 to 15 minutes by showing a positive/negative result to assess the possibility of type I hypersensitivity.
1. This test kit provides scientific evidence which can help veterinarians diagnose allergic disease when dogs exhibit atypical or non-obvious clinical signs.
2. This test kit can assists veterinarians in distinguishing Type I hypersensitivity from other types, allowing for treatment strategies.
3. Can evaluate whether the asymptomatic dog has a tendency to allergy.
4. Can evaluate whether the treatments for the allergic dog is effective.
Canine allergic tendency reference test and diagnosis of allergy
| Note 1: | There are also known cases where the dogs’ binding of IgE and mast cell is strong and therefore they exhibit symptoms without excessive IgE levels. |
| Note 2: | If the test result of asymptomatic dog is positive, it indicates that there is a high tendency of developing clinical sign in the future. If the binding of IgE and mast cell is weak, symptoms may not appear. |
Comparison between Type I and Type IV hypersensitivity
Contact dermatitis is classified as Type IV hypersensitivity, but its clinical signs are similar to those of Type I hypersensitivity (ex: canine atopic dermatitis). Type IV hypersensitivity does not increase IgE in the serum. We can distinguish Type IV hypersensitivity from Type I by detecting tIgE concentrations or observing the response to treatment. However, the “Canine Allergic Tendency Reference Test” is the only tool which can detect levels of IgE in the serum and show the result immediately in the clinic.
However, the “Canine Allergic Tendency Reference Test” should not be used alone to diagnosis allergy, as it is one of the valuable and scientific tools to screening type I hypersensitivity and rule out other possible causes.
